Targeting multidrug resistance in cancer by natural chemosensitizers
نویسندگان
چکیده
منابع مشابه
Overcoming Multidrug Resistance in Human Cancer Cells by Natural Compounds
Multidrug resistance is a phenomenon whereby tumors become resistant to structurally unrelated anticancer drugs. P-glycoprotein belongs to the large ATP-binding cassette (ABC) transporter superfamily of membrane transport proteins. P-glycoprotein mediates resistance to various classes of anticancer drugs including vinblastine, daunorubicin, and paclitaxel, by actively extruding the drugs from t...
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ژورنال
عنوان ژورنال: Bulletin of the National Research Centre
سال: 2019
ISSN: 2522-8307
DOI: 10.1186/s42269-019-0043-8